Ravi Parikh, MD, MPP, FACP, of Emory University and the Editor-in-Chief of ASCO AI in Oncology, spoke with Melina E. Marmarelis, MD, MSCE, of the University of Pennsylvania, during the 2026 ASCO Annual Meeting about her poster presentation, which was a multi-center prospective study looking at the use of an AI-enabled clinical decision support system to identify and help close gaps in biomarker testing for patients with early-stage non–small cell lung cancer (NSCLC). The program resulted in clinically meaningful improvements in biomarker testing rates from baseline for EGFR, ALK, and PD-L1 expression in patients with early NSCLC across six community health systems, and shortened times from diagnosis to testing.